Palo santo (Bursera graveolens) is a tree that's native to Peru, Ecuador, and other South American countries. It grows in dry tropical forests and produces very fragrant resin. In Spanish, palo santo means “holy wood.” For thousands of years, the wood, resin, and oil have been used for sacred purposes. It’s also said to clear negative energy. There isn’t a lot of scientific proof behind these benefits. Nevertheless, palo santo has been used by indigenous peoples for centuries.